What is Abdominal Pain and Discomfort

Abdominal pain is one of the most common reasons people seek medical care. It can range from mild, fleeting discomfort after a large meal to severe, persistent pain that suggests a serious underlying condition. The abdomen houses multiple organs—including the stomach, intestines, liver, gallbladder, pancreas, and spleen—so pinpointing the exact cause often requires careful evaluation by a healthcare professional.

Common Causes

  • Digestive disorders such as gastritis, peptic ulcer disease, gallstones, or pancreatitis.
  • Inflammatory conditions like appendicitis, diverticulitis, or inflammatory bowel disease (Crohn’s disease or ulcerative colitis).
  • Functional disorders including irritable bowel syndrome or functional dyspepsia.
  • Constipation, gas, or indigestion.
  • Non‑gastrointestinal causes such as urinary tract infections, gynecologic problems, or musculoskeletal strain.

When to Seek Care

  • Severe or worsening pain, especially if it comes on suddenly.
  • Persistent pain lasting more than a few hours.
  • Pain accompanied by fever, vomiting, or inability to keep food or liquids down.
  • Blood in vomit or stool, black tarry stools, or unexplained weight loss.
  • Pain during pregnancy or in someone with a history of abdominal surgery.

Diagnosis & Tests

  • Careful review of your medical history and physical examination.
  • Blood and urine tests to look for infection, inflammation, or metabolic disorders.
  • Imaging studies such as ultrasound, CT scan, or MRI to evaluate organs and detect abnormalities.
  • Endoscopic procedures (upper endoscopy or colonoscopy) to directly visualize the digestive tract.
  • Specialized tests depending on suspected conditions (e.g., pregnancy test, stool studies).

Treatment

  • Treatment depends on the underlying cause and may include dietary adjustments, hydration, and rest.
  • Medications to relieve pain, reduce stomach acid, control inflammation, or treat infection.
  • Procedures such as removal of gallstones, appendectomy, or endoscopic interventions.
  • Surgery for serious conditions such as perforated ulcers, appendicitis, or bowel obstruction.
  • Follow‑up care and lifestyle changes to prevent recurrence or manage chronic conditions.

Gold Standard References

American Academy of Family Physicians. (2023).
Acute abdominal pain in adults: Evaluation and diagnosis.
American Family Physician, 107(6), 607–616.

https://www.aafp.org/pubs/afp/issues/2023/0600/acute-abdominal-pain-adults.html

Cartwright, S. L., & Knudson, M. P. (2008).
Evaluation of acute abdominal pain in adults.
American Family Physician, 77(7), 971–978.

https://www.aafp.org/pubs/afp/issues/2008/0401/p971.html

Mayo Clinic Staff. (2023).
Abdominal pain: Causes.
Mayo Clinic.

https://www.mayoclinic.org/symptoms/abdominal-pain/basics/causes/sym-20050728

National Center for Biotechnology Information. (2022).
Acute abdomen.
In StatPearls. StatPearls Publishing.

https://www.ncbi.nlm.nih.gov/books/NBK459328/

New England Journal of Medicine. (2023).
Acute abdomen in the modern era.
The New England Journal of Medicine, 389(21), 1911–1920.

https://doi.org/10.1056/NEJMra2304821